Feb - Rob Holt and Rene Warren¶
Speaker: Rob Holt and Rene Warren
Event Details
Date/Time: **Please note the change!!¶
Wednesday, February 13, 2007, 6:00pm
Talk Title Exploring ectopic expression in E.coli hybrid cells
Affiliation: Genome Sciences Centre
URL: Rob Holt
Abstract:
Engineered microbes are of great potential utility in biotechnology and basic research. For whole genome engineering, compatibilities of genetic material between microbes must be explored. We have developed a system for constructing large episomal elements in E.coli and have reassembled portions of the H.influenzae genome in an E.coli host, with the long term aim complete genome exchange. We have explored gene incompatibilities between E.coli, H.flu and other bacteria, and we have gathered extensive data on expression of exogenous DNA in E.coli that suggests cross-talk in gene regulation between E.coli and other organisms is extensive. These results will be discussed.
Introductory Speaker: ### Chi Kin Ho
Talk Title: Computationally identifying novel essential genes, including non-coding RNAs, in intergenic sequences in bacterial genomes
Affiliation: Brinkman Lab, SFU