Talk Title:
Human Genome Structural Variation, Disease and Evolution
Date/Time:
Wednesday, January 13, 2010, 6:00pm **NOTE DATE CHANGE**
Affiliation:
Department of Genome Sciences, HHMI, University of Washington, Seattle
URL:
Evan Eichler
Abstract:
Structural variation of the genome is an important aspect in our understanding of
human disease and evolution. Accurately characterizing such variation an unmet
challenge of both bioinformatics and genomics. I will focus on the genome-wide
discovery, analysis and distribution of copy-number variants (CNV) and inversion
polymorphisms within human and great ape species. I will present methods to
accurately resolve the copy, content and structure of these regions based on
traditional and next-generation sequence datasets. I will discuss our efforts to
characterize regions of the genome that are prone to recurrent deletion, duplication
and inversion and provide examples of their importance as recurrent and de novo
sources of neuropsychiatric and neurocognitive disease.
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Introductory Speaker:
Parisa Shooshtari
Talk Title:
Faithful Sampling for Spectral Clustering to Analyse High Throughput Flow Cytometry Data
Affiliation:
School of Computing Science, Simon Fraser University
Supervisor: Drs. Arvind Gupta and Ryan Brinkman
The upcoming 2009-2010 meeting dates
February, 2010 **NO VANBUG DUE TO OLYMPIC WINTER GAMES**
March 11, 2010 Main Speaker: Rich Bonneau , New York University; Intro Speaker: TBD
April 8, 2010 Main Speaker: Joerg Gsponer , Centre for High-Throughput Biology; Intro Speaker: Kieran O’Neill, Brinkman Lab, BCCRC
